A. Make sure that all substrates are level, dry, and clean. This is very important for the long-term health of the structure and the overall performance and look of the glass tile you’ve chosen to install. Sandpaper the area to clear it of any residual materials which might affect how well the tile will bond with the substrate. Generally, glass tile will adhere to nearly any type of material – wood, metal, plasterboard, more. The key to success, after the substrate has been prepared, is choosing the right kind of adhesive.